[Validation of food frequency questionnaire to assess folate intake status in breast cancer patients]

Inadequate folate intake could be associated with increased breast cancer risk. The aim of the present study was to assess the folate intake by designed Food Frequency Questionnaire [FFQ] using plasma folate concentration. This analytic cross-sectional study was conducted to evaluate the validity of the semi-quantitative FFQ [136 items] in 152 women with confirmed breast malignancy aged between 35 - 85 years old.. Folate plasma level was assessed by means of automated electrochemiluminescence. The Pearson and partial correlation coefficients were performed between the plasma level of folate and crude, total and energy-adjusted [residual] folate intakes. Area under ROC curve [AUC], sensitivity, specificity, positive and negative predictive values and odds ratio were fulfilled in two models in order to achieve validity assessment. The folate plasma level was significantly correlated with total intake of vegetables, bread and cereal groups [p=0.001] and also with total intake of fruits [p=0.001] and dairy products [p=0.026]. After adjusting for confounders, the folate plasma levels were correlated significantly with daily [beta=0.39], and residual [beta=0.41] folate intake levels [p=0.001]. The area under ROC curves in model I [folate plasma level <5.9 ng/ml] was 0.74 [95%CI=0.63-0.85] and for model II [folate plasma level <10.0 ng/ml] was estimated as 0.61[95%CI= 0.51- 0.71]. Model I indicated more appropriate predictive value [p=0.001] of folate intake assessment via FFQ. The results of this study showed that FFQ described in this study could be a valid and appropriate tool for assessing folate intake status in dietary content of breast cancer patients and also could be representative and valid for assessing the folate rich-food intake status

[ effect of education based on health belief model on preventive factors of osteoporosis among postmenopausal women]

Osteoporosis and the fractures associated with are a major public health concern, because of related morbidity and disability, diminished quality of life, and mortality. Evidence suggests that to adopt changes on some life styles can prevent or delay development of osteoporosis. Most important modifiable risk factors of osteoporosis are receiving inadequate calcium intake and not doing weight-bearing exercises such as walking. The aim of this study was to determine the effect of an educational program based on health belief model on preventive factors of osteoporosis among postmenopausal women. This study was a quasi-experimental research with two groups, experimental [n=43] and control [n=41] selected from 4 mosques situated in ray city. The subjects in experimental group participated in a 6-week educational program [each session 60-90 minutes] based on health belief model. Data collection tools included demographic information form, knowledge questionnaire, health belief scale and food frequency questionnaire which were completed by the subjects of two groups before and after intervention. The authors declare that they have no conflict of interests. Before intervention, there was no statistically significant difference between two groups regarding demographic characteristics, knowledge, health belief constructs, calcium intake and walking. After intervention, t-test showed a statistically significant difference between two groups in perceived susceptibility and severity [P<0.0001], barriers of calcium intake [P<0.0001], and barriers of exercise [P<0.0001]. Perceived benefits of calcium intake and exercise were not significantly different between groups after intervention [P=0.06]. Dietary Calcium intake increased to 906.55 +/- 282.45 mg/day in experimental group, but there was not statistically significant difference between two groups [P=0.40]. Changes in frequency of weekly walking was statistically significant [p=0.005] between groups, but the total time of walking wasn't statistically significant between them [P=0.07]. Educational program based on health belief model was effective in increasing health belief constructs and walking frequency but not in dietary calcium intake